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For vaccines, the agency said that if a product that has already received emergency use authorization needs modification to address the variant, guidance recommends that a determination of efficacy be supported by data from clinical immunogenicity studies, which would compare a recipient’s immune response to virus variants induced by the modified vaccine against the immune response to the authorized vaccine. casio mdv 160 Meanwhile, the order also directs Director of National Intelligence Avril Haines to prepare a National Intelligence Estimate on the security implications of climate change, the State Department to prepare a transmittal package to the Senate for the Kigali Amendment to the Montreal protocol, and all agencies to develop strategies for integrating climate considerations into their international work. casio mdv 160 Marco Rubio: Put students first and open schools – here's what we should do if teacher unions refuseGrover Norquist: Pelosi, Schumer priorities – here's how free speech, fair elections and more at riskLiz Peek: Biden's first 10 days – here's how he infuriated half the nation in record timeThis isn’t speculation – it’s obvious in President Biden’s choices for some of our most important leadership positions. casio mdv 160 nbsp;Instead of acting to heal the nation, or at the very least focusing on prosecuting the lawbreakers who stormed the Capitol, the Speaker of the House and her allies have tried to callously harness the chaos of the moment for their own political gain— Trump defense teamTrump's defense team previewed its strategy in a pre-trial brief Monday, slamming the impeachment effort as "political theater. casio mdv 160